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KMID : 1123920020160051009
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Korean Journal of Oriental Physiology and Pathology
2002 Volume.16 No. 5 p.1009 ~ p.1015
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The Studies on the Anti-allergic Property of Yonggak-san
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Rho Jin-Woo
Lee Kwang-Gyu
Lee Chang-Hyun
Yuk Sang-Won
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Abstract
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The purpose of this research was to investigate the effect of Yonggak-san (YGS) on the anti-allergic reaction in vivo and in vitro. Administration of YGS(500 mg/kg) enhanced hemaggutination(HA)titer against SRBC. On the while, YGS inhibited hyaluronidase activity in vitro and passive cutaneous anaphylaxis reaction, lethal anaphylaxis and mortality induced by compound 48/80 in mice, YGS decreased Arthus reaction, acute hind paw edema induced by histamine. But YGS did not affect delayed type hypersensitivity induced by SRBC. These results suggest that YGS have anti-allergic action
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KEYWORD
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Yonggak-san(龍角散), hemaggutination, anaphylaxis, arthus reaction
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